SCHEMBL20202963

SCHEMBL20202963

CCCCCc1ccc(-c2ccc(-c3cc(F)c(OCc4ccc5c(F)c(F)c(F)cc5c4)c(F)c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.43
RARA P10276 2/20 0.43
RARG P13631 1/20 0.43
HSD17B10 Q99714 3/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
MTOR P42345 1/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202947 1.00 RARB (0.43) RARBRARARARGHSD17B10TSHR
SCHEMBL20202942 0.97 RARB (0.39) RARBRARARARGTSHRTP53
SCHEMBL20202953 0.97 RARB (0.39) RARBRARARARGTSHRTP53
SCHEMBL20202961 0.93 RARB (0.42) RARBRARARARGHSD17B10TSHR
SCHEMBL20202952 0.92 FFAR4 (0.34) RARBRARARARGHSD17B10TP53
SCHEMBL20202937 0.92 FFAR4 (0.34) RARBRARARARGHSD17B10TP53
SCHEMBL20202929 0.90 RARB (0.41) RARBRARARARGHSD17B10TSHR
SCHEMBL20202964 0.89 RARB (0.38) RARBRARARARG
SCHEMBL20202936 0.88 FFAR4 (0.35) MAPTESR1LMNAACHEFFAR4
SCHEMBL20202962 0.88 FFAR4 (0.35) MAPTESR1LMNAACHEFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed