SCHEMBL20202939

SCHEMBL20202939

CCCCc1cc(F)c(OCc2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)cc2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 8/20 0.37
RARB P10826 5/20 0.37
RARA P10276 2/20 0.37
RARG P13631 1/20 0.37
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
EIF4A1 P60842 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202929 0.97 RARB (0.41) FFAR4RARBRARARARGESR1
SCHEMBL16210206 0.93 FFAR4 (0.38) FFAR4RARBRARARARGESR1
SCHEMBL20202938 0.90 ESR1 (0.38) FFAR4ESR1ESR2
SCHEMBL20202940 0.90 RARB (0.38) FFAR4RARBESR1ESR2
SCHEMBL20202942 0.90 RARB (0.39) FFAR4RARBRARARARGNPC1
SCHEMBL20202953 0.90 RARB (0.39) FFAR4RARBRARARARGNPC1
SCHEMBL20202964 0.87 RARB (0.38) RARBRARARARG
SCHEMBL20202930 0.87 RARB (0.42) FFAR4RARBRARARARGESR1
SCHEMBL20202963 0.86 RARB (0.43) FFAR4RARBRARARARGESR1
SCHEMBL20202947 0.86 RARB (0.43) FFAR4RARBRARARARGESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed