SCHEMBL20202955

SCHEMBL20202955

CCCCCc1ccc(-c2cc(F)c(OCc3ccc4c(F)c(F)c(F)cc4c3)c(F)c2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.39
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
FFAR4 Q5NUL3 1/20 0.31
GRM2 Q14416 1/20 0.31
GPR3 P46089 1/20 0.31
TLR8 Q9NR97 3/20 0.31
FAAH O00519 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202958 0.97 RARB (0.35) RARBRARARARGFFAR4GRM2
SCHEMBL20202961 0.94 RARB (0.42) RARBRARARARG
SCHEMBL20202930 0.93 RARB (0.42) RARBRARARARGFFAR4FAAH
SCHEMBL20202950 0.93 FFAR4 (0.32) FFAR4GRM2
SCHEMBL20202964 0.91 RARB (0.38) RARBRARARARG
SCHEMBL20202940 0.89 RARB (0.38) RARBFFAR4FAAHPTGS2
SCHEMBL20202954 0.89 KDM1A (0.35) FFAR4
SCHEMBL20202963 0.88 RARB (0.43) RARBRARARARGFFAR4PTGS2
SCHEMBL20202947 0.88 RARB (0.43) RARBRARARARGFFAR4PTGS2
SCHEMBL19082886 0.87 RARB (0.44) RARBRARARARGFFAR4GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed