SCHEMBL20202956

SCHEMBL20202956

CCCCc1ccc(-c2cc(F)c(C(F)(F)Oc3ccc4c(F)c(F)c(F)cc4c3)c(F)c2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.33
GRM2 Q14416 1/20 0.32
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
S1PR1 P21453 3/20 0.32
S1PR3 Q99500 3/20 0.32
APLNR P35414 1/20 0.31
PCSK9 Q8NBP7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202951 0.97 RARB (0.36) RARBGRM2ALOX5APFEN1S1PR1
SCHEMBL17719460 0.94 RARB (0.36) RARBGRM2ALOX5APFEN1S1PR1
SCHEMBL20202949 0.94 GRM2 (0.33) GRM2ALOX5APFEN1
SCHEMBL20202969 0.92 RARB (0.39) RARBGRM2ALOX5APFEN1S1PR1
SCHEMBL20202933 0.91 ALOX5AP (0.36) RARBGRM2ALOX5APFEN1S1PR1
SCHEMBL20202966 0.91 ALOX5AP (0.34) GRM2ALOX5APFEN1
SCHEMBL20202943 0.89 RARB (0.36) RARBS1PR1APLNRPCSK9
SCHEMBL20202971 0.89 RARB (0.36) RARBS1PR1APLNRPCSK9
SCHEMBL3439583 0.89 RARB (0.37) RARBGRM2ALOX5APFEN1S1PR1
SCHEMBL20202932 0.88 RARB (0.37) RARBGRM2ALOX5APFEN1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed