SCHEMBL20202971

SCHEMBL20202971

CCCCc1ccc(-c2ccc(-c3cc(F)c(C(F)(F)Oc4ccc5c(F)c(F)c(F)cc5c4)c(F)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.36
RARA P10276 2/20 0.36
RARG P13631 1/20 0.36
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
PPARD Q03181 1/20 0.32
S1PR1 P21453 1/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
EIF4A1 P60842 4/20 0.31
AKR1C2 P52895 1/20 0.31
AKR1C1 Q04828 1/20 0.31
APLNR P35414 1/20 0.31
PCSK9 Q8NBP7 1/20 0.30
MPL P40238 1/20 0.30
CETP P11597 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202943 1.00 RARB (0.36) RARBRARARARGPPARGPPARA
SCHEMBL20202948 0.97 RARB (0.40) RARBRARARARGPPARGPPARA
SCHEMBL20202965 0.97 RARB (0.40) RARBRARARARGPPARGPPARA
SCHEMBL17083187 0.94 RARB (0.31) RARBRARARARG
SCHEMBL20202970 0.94 RARB (0.31) RARBRARARARG
SCHEMBL17719460 0.93 RARB (0.36) RARBRARARARGS1PR1MPL
SCHEMBL20202969 0.90 RARB (0.39) RARBRARARARGS1PR1TSHR
SCHEMBL20202967 0.90 PPM1A (0.30)
SCHEMBL20202959 0.90 PPM1A (0.30)
SCHEMBL20202935 0.89 GSK3B (0.33) RARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed