SCHEMBL20202935

SCHEMBL20202935

CCCCc1cc(F)c(C(F)(F)Oc2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)cc2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.33
RARB P10826 3/20 0.33
RARA P10276 2/20 0.33
RARG P13631 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202945 0.97 RARB (0.37) GSK3BRARBRARARARG
SCHEMBL20202941 0.93 GSK3B (0.34) GSK3B
SCHEMBL20202928 0.91 GSK3B (0.33) GSK3B
SCHEMBL20202933 0.90 ALOX5AP (0.36) RARB
SCHEMBL20202943 0.89 RARB (0.36) RARBRARARARG
SCHEMBL20202971 0.89 RARB (0.36) RARBRARARARG
SCHEMBL17075778 0.88 ALOX5AP (0.34) GSK3B
SCHEMBL17719460 0.87 RARB (0.36) RARBRARARARG
SCHEMBL20202932 0.87 RARB (0.37) RARBRARARARG
SCHEMBL20202948 0.86 RARB (0.40) RARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed