Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.51 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203100 | 0.85 | MAPK1 (0.53) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL21578091 | 0.84 | MAPK1 (0.59) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL3868966 | 0.82 | RECQL (0.53) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL27593044 | 0.81 | RECQL (0.52) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL804817 | 0.79 | MAPK1 (0.66) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL21578020 | 0.79 | MAPK1 (0.53) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL6300348 | 0.78 | RECQL (0.62) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL5581280 | 0.78 | GRIA1 (0.78) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL64508 | 0.77 | ESR2 (0.66) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL29351258 | 0.77 | ESR2 (0.66) | MAPK1HTTGRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10319920-B2 | Carbazole derivatives and organic light-emitting diodes by using the same | YUAN ZE UNIVERSITY (TW) | 2019-06-11 | — | — | US | disclosed |
| US-20180151808-A1 | CARBAZOLE DERIVATIVES AND ORGANIC LIGHT-EMITTING DIODES BY USING THE SAME | YUAN ZE UNIVERSITY (TW) | 2018-05-31 | — | — | US | disclosed |
| US-20180151808-A1 | CARBAZOLE DERIVATIVES AND ORGANIC LIGHT-EMITTING DIODES BY USING THE SAME | YUAN ZE UNIVERSITY (TW) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10319920-B2 | Carbazole derivatives and organic light-emitting diodes by using the same | CBR3, FBXL19, CSNK1A1L | MAPK1 3208/4885HTT 2983/4885GRIA1 563/4885 |
| US-20180151808-A1 | CARBAZOLE DERIVATIVES AND ORGANIC LIGHT-EMITTING DIODES BY USING THE SAME | CBR3, FBXL19, CSNK1A1L | MAPK1 3208/4885HTT 2983/4885GRIA1 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.