Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.52 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21578020 | 0.94 | MAPK1 (0.53) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL20203100 | 0.91 | MAPK1 (0.53) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL21578117 | 0.87 | MAPK1 (0.47) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL804817 | 0.84 | MAPK1 (0.66) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL20203098 | 0.84 | MAPK1 (0.53) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL647306 | 0.81 | RECQL (0.64) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL16280947 | 0.80 | MAPK1 (0.65) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL804992 | 0.80 | ESR2 (0.73) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL541157 | 0.80 | ESR2 (0.78) | MAPK1HTTESR2ESR1RECQL | |
| SCHEMBL13085156 | 0.80 | RECQL (0.71) | MAPK1HTTESR2ESR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190355908-A1 | Organic Cocrystal and Applications of the Same | HU WENPING (CN) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190355908-A1 | Organic Cocrystal and Applications of the Same | OTC, SOD1, AOC1 | MAPK1 3390/4885HTT 2164/4885ESR2 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.