Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203363 | 0.89 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187446 | 0.85 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187635 | 0.84 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL29434778 | 0.81 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187549 | 0.81 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187528 | 0.79 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL21367583 | 0.79 | TRPA1 (0.60) | TRPA1 | |
| SCHEMBL20189034 | 0.78 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187521 | 0.75 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20187542 | 0.75 | TRPA1 (1.00) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096159-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-31 | — | — | WO | disclosed |