Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 11/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806168 | 0.71 | PDCD1 (0.47) | PDCD1CD274 | |
| SCHEMBL20249376 | 0.69 | PDCD1 (0.47) | PDCD1CD274 | |
| SCHEMBL20203445 | 0.67 | CDK4 (0.39) | — | |
| SCHEMBL20203452 | 0.65 | FLT3 (0.47) | PDCD1CD274 | |
| SCHEMBL20203549 | 0.65 | SMO (0.41) | GAAKMT2A | |
| SCHEMBL25725592 | 0.64 | PANK3 (0.41) | — | |
| SCHEMBL18806155 | 0.63 | CDK4 (0.44) | — | |
| SCHEMBL20249151 | 0.62 | GAA (0.47) | GAAKMT2ARXFP1 | |
| SCHEMBL13466378 | 0.61 | DRD2 (0.47) | — | |
| SCHEMBL20203491 | 0.61 | PDCD1 (0.36) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097297-A1 | PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2018-05-31 | — | — | WO | disclosed |