Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733423 | 0.90 | TP53 (0.45) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL20203626 | 0.89 | TP53 (0.40) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL23733440 | 0.87 | MAPK1 (0.39) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL20203627 | 0.87 | RXFP1 (0.43) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL20203533 | 0.84 | TP53 (0.36) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL20203618 | 0.83 | TDP1 (0.39) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL20037634 | 0.82 | TDP1 (0.43) | POLBALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL18291265 | 0.82 | KMT2A (0.42) | POLBALDH1A1TDP1MAPTTP53 | |
| SCHEMBL31164152 | 0.82 | KMT2A (0.42) | POLBALDH1A1TDP1MAPTTP53 | |
| SCHEMBL20203620 | 0.81 | JAK2 (0.40) | POLBALDH1A1TDP1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097297-A1 | PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2018-05-31 | — | — | WO | disclosed |