SCHEMBL2020371

SCHEMBL2020371

Cc1nnc(N2CCC[C@@H](N)C2)n(Cc2cc(F)ccc2C#N)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 1.00
KCNH2 Q12809 1/20 0.63
FAP Q12884 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020372 1.00 DPP4 (1.00) DPP4KCNH2FAP
Benzoic Acid SCHEMBL28645610 0.92 DPP4 (1.00) DPP4KCNH2FAP
SCHEMBL2024039 0.87 DPP4 (0.77) DPP4FAP
SCHEMBL2023363 0.87 DPP4 (0.77) DPP4
SCHEMBL2024037 0.87 DPP4 (0.77) DPP4FAP
SCHEMBL2023360 0.87 DPP4 (0.77) DPP4
SCHEMBL2027764 0.87 DPP4 (0.78) DPP4
SCHEMBL2027763 0.87 DPP4 (0.78) DPP4
SCHEMBL28636345 0.87 DPP4 (0.76) DPP4KCNH2FAP
SCHEMBL2201273 0.86 DPP4 (0.76) DPP4KCNH2FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694979-A2 COMPOUNDS FOR UPREGULATING UTROPHIN LEVELS IN MUSCLE CELLS AND METHOD OF APPLICATION THEREOF Peptris Technologies Private Limited (IN) 2026-02-18 EP claimed
EP-4554574-A2 SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES The Scripps Research Institute (US) 2025-05-21 EP claimed
WO-2025057088-A1 RNA COMPOSITIONS FOR DELIVERY OF INCRETIN AGENTS BioNTech SE (DE) 2025-03-20 WO claimed
WO-2024214117-A2 COMPOUNDS FOR UPREGULATING UTROPHIN LEVELS IN MUSCLE CELLS AND METHOD OF APPLICATION THEREOF PEPTRIS TECHNOLOGIES PRIVATE LIMITED (IN) 2024-10-17 WO claimed
US-20240115577-A1 SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES THE SCRIPPS RESEARCH INSTITUTE 2024-04-11 US claimed
WO-2024015889-A2 SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES THE SCRIPPS RESEARCH INSTITUTE (US) 2024-01-18 WO claimed
US-11519034-B2 Non-invasive diagnostic of non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis and/or liver fibrosis GENFIT (FR) 2022-12-06 US claimed
EP-2521721-B1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2014-10-01 EP claimed
US-8648073-B2 Certain dipeptidyl peptidase inhibitors FOCHON PHARMA, INC. (US) 2014-02-11 US claimed
EP-2521721-A1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS Shanghai Fochon Pharmaceutical Co. Ltd (CN) 2012-11-14 EP claimed
WO-2011079778-A1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2011-07-07 WO claimed
EP-4735023-A2 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE Piton Therapeutics, Inc. (US) 2026-05-06 EP disclosed
EP-3985126-B1 NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC STEATOHEPATITIS GENFIT (FR) 2026-03-04 EP disclosed
CN-121586585-A Compounds for up-regulating myotrophic related protein levels in muscle cells and methods of use thereof 肽智科技私人有限公司 2026-02-27 CN disclosed
EP-4694979-A2 COMPOUNDS FOR UPREGULATING UTROPHIN LEVELS IN MUSCLE CELLS AND METHOD OF APPLICATION THEREOF Peptris Technologies Private Limited (IN) 2026-02-18 EP disclosed
EP-2521721-A1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS Shanghai Fochon Pharmaceutical Co. Ltd (CN) 2012-11-14 EP disclosed
WO-2011079778-A1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2011-07-07 WO disclosed
US-20110160212-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS FOCHON PHARMA, INC. 2011-06-30 US disclosed
US-20110160212-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS FOCHON PHARMA, INC. 2011-06-30 US disclosed
US-20110160212-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS FOCHON PHARMA, INC. 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160212-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS DPP4, DPP3, DPP8 DPP4 1/4885KCNH2 4352/4885FAP 9/4885
US-20240115577-A1 SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES DPP4, DPP7, ING2 DPP4 1/4885KCNH2 4421/4885FAP 850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.