Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022446 | 0.90 | DPP4 (0.69) | DPP4FAP | |
| SCHEMBL2022448 | 0.90 | DPP4 (0.69) | DPP4FAP | |
| SCHEMBL2181463 | 0.89 | DPP4 (0.61) | DPP4CYP3A4 | |
| SCHEMBL2201252 | 0.87 | DPP4 (0.57) | DPP4CYP3A4FAP | |
| SCHEMBL2200504 | 0.87 | DPP4 (0.57) | DPP4CYP3A4FAP | |
| SCHEMBL2020372 | 0.86 | DPP4 (1.00) | DPP4KCNH2FAP | |
| SCHEMBL2020371 | 0.86 | DPP4 (1.00) | DPP4KCNH2FAP | |
| Benzoic Acid SCHEMBL28645610 | 0.84 | DPP4 (1.00) | DPP4CYP3A4KCNH2FAP | |
| SCHEMBL28636345 | 0.84 | DPP4 (0.76) | DPP4KCNH2FAP | |
| SCHEMBL28461817 | 0.81 | DPP4 (0.60) | DPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521721-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | Shanghai Fochon Pharmaceutical Co. Ltd (CN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011079778-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2011-07-07 | — | — | WO | disclosed |