Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203975 | 0.93 | SCN5A (0.52) | ADORA3SCN5ACYP1A2DYRK1ASCN1A | |
| SCHEMBL26539438 | 0.82 | SCN5A (0.46) | SCN5ACYP1A2SCN1ASCN2A | |
| SCHEMBL26539425 | 0.80 | ADORA3 (0.49) | ADORA3SCN5ACYP1A2DYRK1AFYN | |
| SCHEMBL26539447 | 0.80 | SCN5A (0.50) | SCN5ACYP1A2SCN1ASCN2AMAPT | |
| SCHEMBL26539329 | 0.80 | SCN5A (0.50) | SCN5ACYP1A2SCN1ASCN2AMAPT | |
| SCHEMBL26539353 | 0.79 | SCN5A (0.49) | SCN5ACYP1A2SCN1ASCN2AMAPT | |
| SCHEMBL26539455 | 0.79 | SCN5A (0.49) | SCN5ACYP1A2SCN1ASCN2AMAPT | |
| SCHEMBL26539441 | 0.78 | SCN5A (0.46) | SCN5ACYP1A2SCN1ASCN2AMAPT | |
| SCHEMBL26539323 | 0.75 | CYP1A2 (0.49) | SCN5ACYP1A2DYRK1ASCN1ASCN2A | |
| SCHEMBL20203717 | 0.73 | CYP1A2 (0.54) | ADORA3SCN5ACYP1A2DYRK1ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
| WO-2018098499-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | ADORA3 2285/4885SCN5A 8/4885CYP1A2 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.