Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393598 | 0.81 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2PTGS1PTGS2SCN9A | |
| SCHEMBL20203893 | 0.80 | L3MBTL1 (0.41) | L3MBTL1MBOAT4SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL15901388 | 0.80 | HPGD (0.37) | MBOAT4SMN1; SMN2TDP1POLBADORA2A | |
| SCHEMBL28393739 | 0.78 | L3MBTL1 (0.39) | L3MBTL1ULK1SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL2715306 | 0.78 | CD274 (0.43) | L3MBTL1MBOAT4SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL2715167 | 0.78 | L3MBTL1 (0.40) | L3MBTL1MBOAT4SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL23414825 | 0.78 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2CYP1A2POLBHPGDS | |
| Hydrochloric Acid SCHEMBL2716920 | 0.77 | CD274 (0.42) | L3MBTL1MBOAT4SMN1; SMN2PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL28390283 | 0.77 | L3MBTL1 (0.38) | L3MBTL1ULK1SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL21411445 | 0.77 | L3MBTL1 (0.37) | L3MBTL1ULK1MBOAT4SMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
| WO-2018098499-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | L3MBTL1 1392/4885ULK1 4267/4885MBOAT4 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.