Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20190711 | 1.00 | CYP1A2 (0.42) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20190491 | 1.00 | CYP1A2 (0.42) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20204003 | 0.87 | CYP1A2 (0.39) | CYP1A2 | |
| SCHEMBL20203837 | 0.82 | CYP1A2 (0.43) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20190811 | 0.82 | CYP1A2 (0.43) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20190944 | 0.82 | CYP1A2 (0.43) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20203930 | 0.81 | CYP1A2 (0.60) | CYP1A2SCN5ASCN1ASCN2AEPHX2 | |
| SCHEMBL20190332 | 0.78 | PRKDC (0.49) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20190550 | 0.78 | PRKDC (0.49) | CYP1A2SCN5ASCN1ASCN2APIK3CB | |
| SCHEMBL20191057 | 0.78 | PRKDC (0.49) | CYP1A2SCN5ASCN1ASCN2APIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098499-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |