SCHEMBL20204094

SCHEMBL20204094

COCC(c1ccc([N+](=O)[O-])cc1)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
CYP1A2 P05177 1/20 0.46
TSHR P16473 1/20 0.46
PHLPP2 Q6ZVD8 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HSD17B10 Q99714 2/20 0.45
ACHE P22303 1/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
TP53 P04637 1/20 0.45
THRB P10828 1/20 0.45
NPC1 O15118 2/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CNR1 P21554 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10880051 0.81 ALDH1A1 (0.44) ALDH1A1MAPTCYP3A4MAPK1CYP1A2
SCHEMBL7607677 0.80 NPC1 (0.50) ALDH1A1MAPTMAPK1TDP1LMNA
SCHEMBL118823 0.79 ALDH1A1 (0.45) ALDH1A1MAPTCYP3A4MAPK1CYP1A2
SCHEMBL118824 0.79 ALDH1A1 (0.45) ALDH1A1MAPTCYP3A4MAPK1CYP1A2
SCHEMBL27520363 0.77 GRM8 (0.44) ALDH1A1MAPTCYP3A4MAPK1CYP1A2
SCHEMBL6262313 0.76 CA1 (0.51) ALDH1A1MAPTTDP1L3MBTL1ACHE
SCHEMBL1321714 0.76 NPSR1 (0.47) ALDH1A1MAPTCYP3A4CYP1A2TSHR
SCHEMBL8607054 0.76 ALDH1A1 (0.46) ALDH1A1MAPTCYP3A4TDP1LMNA
SCHEMBL4787856 0.76 CNR1 (0.50) ALDH1A1MAPTCYP3A4MAPK1CYP1A2
SCHEMBL27287540 0.75 ALDH1A1 (0.45) ALDH1A1MAPTCYP3A4MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10731004-B2 Polyimide precursor composition and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-08-04 US disclosed
US-10696793-B2 Process for preparing polyimides ETERNAL MATERIALS CO., LTD. (TW) 2020-06-30 US disclosed
US-10626220-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-04-21 US disclosed
US-20200055986-A1 PROCESS FOR PREPARING POLYIMIDES ETERNAL MATERIALS CO., LTD. (TW) 2020-02-20 US disclosed
US-20180148541-A1 POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148544-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIAL CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148544-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIAL CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148541-A1 POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-05-31 US disclosed