⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016706 | 0.88 | — | — | |
| SCHEMBL23982848 | 0.85 | — | — | |
| SCHEMBL18473113 | 0.82 | — | — | |
| SCHEMBL19646932 | 0.81 | — | — | |
| SCHEMBL23836631 | 0.81 | — | — | |
| SCHEMBL23982988 | 0.80 | — | — | |
| SCHEMBL18790800 | 0.80 | TAS2R38 (0.33) | — | |
| SCHEMBL21654953 | 0.79 | — | — | |
| SCHEMBL18913909 | 0.79 | — | — | |
| SCHEMBL18626259 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040803-B2 | 4-((2-acrylamidophenyl)amino)thieno[3,2-D]pyrimidine-7-carboxamide derivatives as protein kinase inhibitors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-08-07 | — | — | US | disclosed |
| US-20180148459-A1 | 4-((2-ACRYLAMIDOPHENYL)AMINO)THIENO[3,2-D]PYRIMIDINE-7-CARBOXAMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-05-31 | — | — | US | disclosed |