Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 17/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870778 | 0.92 | DUT (0.64) | DUTPOLBKMT2AHTTGAA | |
| SCHEMBL20374431 | 0.81 | DUT (0.63) | DUT | |
| SCHEMBL20204782 | 0.81 | DUT (0.68) | DUTGAA | |
| SCHEMBL21536598 | 0.81 | DUT (0.70) | DUT | |
| SCHEMBL1409352 | 0.80 | DUT (0.67) | DUT | |
| SCHEMBL27827503 | 0.78 | DUT (0.65) | DUT | |
| SCHEMBL1410044 | 0.77 | DUT (1.00) | DUT | |
| SCHEMBL12629734 | 0.73 | DUT (0.75) | DUT | |
| SCHEMBL21536721 | 0.73 | DUT (0.71) | DUT | |
| SCHEMBL21536674 | 0.73 | DUT (0.60) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |