Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328806 | 1.00 | L3MBTL1 (0.35) | L3MBTL1TDP1GAATSHRF2 | |
| SCHEMBL28178801 | 0.82 | GAA (0.32) | TDP1GAAHSD17B10 | |
| SCHEMBL27082357 | 0.79 | GAA (0.47) | TDP1GAALMNA | |
| SCHEMBL2984708 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL7044026 | 0.76 | PIK3CD (0.42) | TSHR | |
| SCHEMBL12099149 | 0.74 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL1362820 | 0.74 | L3MBTL1 (0.34) | L3MBTL1TSHR | |
| SCHEMBL6234245 | 0.74 | L3MBTL1 (0.39) | L3MBTL1HSD17B10 | |
| SCHEMBL20187928 | 0.74 | MAPT (0.40) | L3MBTL1TDP1GAA | |
| SCHEMBL20187930 | 0.74 | MAPT (0.40) | L3MBTL1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |