Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090820 | 1.00 | PDE7A (0.73) | PDE7AMEN1KMT2ATTRALB | |
| SCHEMBL29780387 | 0.90 | PDE7A (0.82) | PDE7AMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL5863266 | 0.90 | PDE7A (0.82) | PDE7AMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL9174802 | 0.87 | MEN1 (0.60) | PDE7AMEN1KMT2ATTRALB | |
| SCHEMBL10387432 | 0.86 | PDE7A (0.71) | PDE7AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11475236 | 0.86 | PDE7A (0.76) | PDE7AMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL10824979 | 0.85 | PDE7A (0.66) | PDE7AMEN1KMT2ATTRALB | |
| SCHEMBL2961786 | 0.84 | PDE7A (0.74) | PDE7AMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL810516 | 0.84 | PDE7A (0.74) | PDE7AMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL2016906 | 0.84 | PDE7A (0.68) | PDE7AMEN1KMT2ATTRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388379-A | Organic total synthesis method of nimesulide derivative | 大连理工大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-115124463-B | Substituted quinoline compound and preparation method and application thereof | 浙江工业大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-115124463-A | Substituted quinoline compound and preparation method and application thereof | 浙江工业大学 | 2022-09-30 | — | — | CN | disclosed |
| US-8338605-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2012-12-25 | — | — | US | disclosed |
| US-8236950-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2012-08-07 | — | — | US | disclosed |
| US-20110160233-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |
| US-20100256139-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2010-10-07 | — | — | US | disclosed |
| EP-1979349-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2010-07-28 | — | — | EP | disclosed |
| US-7763731-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2010-07-27 | — | — | US | disclosed |
| EP-2094276-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-1979349-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| US-20070232645-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2007-10-04 | — | — | US | disclosed |
| WO-2007076035-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |
| US-5382686-A | Process for preparing nitrodiphenyl (thio) ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| US-5324722-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1993013082-A1 | SUBSTITUTED DIBENZOXAZEPINES OR DIBENZOTHIAZEPINES AND THEIR USE AS PROSTAGLANDIN E2 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0304725-B1 | PROCESS FOR THE PREPARATION OF NITRO-DIPHENYL(THIO) ETHERS | BAYER AG (DE) | 1992-01-22 | — | — | EP | disclosed |
| EP-0304725-A1 | Process for the preparation of nitro-diphenyl(thio) ethers | BAYER AG (DE) | 1989-03-01 | — | — | EP | disclosed |
| US-4478852-A | FUNGICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4059627-A | HYDROGENATION OF CHLORINATED NITRO AROMATIC, NOBLE METAL CATALYST, THIOETHER | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160233-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, MAVS, EIF2AK2 | PDE7A 4223/4885MEN1 4571/4885KMT2A 3566/4885 |
| US-20070232645-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, MAVS, EIF2AK2 | PDE7A 4223/4885MEN1 4571/4885KMT2A 3566/4885 |
| US-20100256139-A1 | Anti-Viral Compounds | HAVCR2, MAVS, EIF2AK2 | PDE7A 4223/4885MEN1 4571/4885KMT2A 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.