SCHEMBL20205303

SCHEMBL20205303

CC1(C)c2ccccc2-c2ccc(-c3cc4c(c5c3oc3ccccc35)-c3ccc5c(c3[Si]4(C)C)[Si](C)(C)c3cc(-c4ccc6c(c4)C(C)(C)c4ccccc4-6)c4c(oc6ccccc64)c3-5)cc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20205550 0.98 — —
SCHEMBL20205482 0.96 ALOX5 (0.33) ALOX5
SCHEMBL24649900 0.96 ALOX5 (0.33) ALOX5
SCHEMBL24649895 0.95 ALOX5 (0.30) ALOX5
SCHEMBL20205562 0.94 ALOX5 (0.32) ALOX5
SCHEMBL23351762 0.93 ALOX5 (0.31) ALOX5
SCHEMBL20205733 0.92 — —
SCHEMBL20205526 0.92 ALOX5 (0.30) ALOX5
SCHEMBL20205570 0.91 ALOX5 (0.32) ALOX5
SCHEMBL24649896 0.91 ALOX5 (0.32) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11453680-B2 Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2022-09-27 — — US disclosed
WO-2018095940-A1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11453680-B2 Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD2, OCIAD1, JUND ALOX5 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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