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SCHEMBL20205549

SCHEMBL20205549

CC1(C)c2ccccc2-c2cc3c(cc21)-c1ccc(-c2cc4c(c5oc6ccccc6c25)-c2cc5c(cc2C4(C)C)-c2c(cc(-c4ccc6c(c4)C(C)(C)c4cc7c(cc4-6)C(C)(C)c4ccccc4-7)c4c2oc2ccccc24)C5(C)C)cc1C3(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.36
▸ ALK Q9UM73 5/20 0.33
▸ PGR P06401 1/20 0.32
▸ PDK2 Q15119 2/20 0.31
▸ CDC14B O60729 2/20 0.31
▸ CDC14A Q9UNH5 2/20 0.31
▸ PRKDC P78527 1/20 0.30
▸ GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20205722 0.99 ALOX5 (0.37) ALOX5ALKPGRPDK2CDC14B
SCHEMBL20205294 0.96 ALOX5 (0.34) ALOX5ALKCDC14BCDC14A
SCHEMBL20205723 0.95 ALOX5 (0.36) ALOX5ALKPGRPRKDCGGPS1
SCHEMBL24649657 0.94 ALOX5 (0.37) ALOX5ALKPRKDCGGPS1
SCHEMBL20205293 0.94 ALOX5 (0.34) ALOX5ALKPGRCDC14BCDC14A
SCHEMBL20205664 0.93 ALOX5 (0.38) ALOX5ALKPDK2PRKDC
SCHEMBL22389277 0.93 PDK2 (0.34) ALOX5ALKPGRPDK2
SCHEMBL24649624 0.93 ALOX5 (0.32) ALOX5ALK
SCHEMBL20205291 0.91 ALOX5 (0.34) ALOX5ALK
SCHEMBL23351580 0.91 ALOX5 (0.36) ALOX5ALKPGRPDK2CDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3544985-B1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2021-05-12 — — EP disclosed
WO-2018095940-A1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 — — WO disclosed
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