SCHEMBL202057

SCHEMBL202057

CCOC(=O)CC1(C)CC2C=CC1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 3/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
ALDH1A1 P00352 5/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
TRPA1 O75762 1/20 0.32
EPHX2 P34913 2/20 0.32
ALOX15 P16050 2/20 0.31
USP2 O75604 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4257617 0.85 CYP2D6 (0.36) CYP2D6CYP2C19KMT2AGAAMGAM
SCHEMBL4270319 0.84 CYP2D6 (0.36) CYP2D6CYP2C19EPHX2
SCHEMBL32688724 0.83 EPHX2 (0.34) CYP2D6CYP2C19GAAALDH1A1EPHX2
SCHEMBL5358484 0.81 ALDH1A1 (0.38) CYP2D6CYP2C19ALDH1A1LMNA
SCHEMBL11759558 0.79 CYP2D6 (0.36) CYP2D6CYP2C19KMT2AL3MBTL1GAA
SCHEMBL5838108 0.79 CYP2D6 (0.36) CYP2D6CYP2C19KMT2AL3MBTL1GAA
SCHEMBL5837507 0.79 CYP2D6 (0.36) CYP2D6CYP2C19KMT2AL3MBTL1GAA
SCHEMBL11755667 0.79 CYP2D6 (0.36) CYP2D6CYP2C19KMT2AL3MBTL1GAA
SCHEMBL2873491 0.79 CYP2D6 (0.39) CYP2D6CYP2C19KDM4E
SCHEMBL5837108 0.77 CYP2D6 (0.35) CYP2D6CYP2C19KMT2AL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-7049220-B2 Method of forming cavity between multilayered wirings JSR CORPORATION (JP) 2006-05-23 US disclosed
US-7015293-B2 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2006-03-21 US disclosed
US-20050171310-A1 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2005-08-04 US disclosed
EP-1538169-A1 CYCLOOLEFIN ADDITION COPOLYMER AND OPTICAL TRANSPARENT MATERIAL JSR Corporation (JP) 2005-06-08 EP disclosed
US-20040132243-A1 Method of forming cavity between multilayered wirings JSR CORPORATION (JP) 2004-07-08 US disclosed
EP-1416528-A2 Method of forming cavity between multilayered wirings JSR Corporation (JP) 2004-05-06 EP disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed