⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814475 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL5907560 | 0.78 | — | — | |
| SCHEMBL2018465 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL20920025 | 0.76 | — | — | |
| SCHEMBL20920023 | 0.76 | — | — | |
| SCHEMBL12219493 | 0.75 | — | — | |
| SCHEMBL9452628 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL2371528 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL20919831 | 0.74 | TET2 (0.40) | — | |
| SCHEMBL5690075 | 0.74 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776522-B | Substituted heteroaryl compounds, compositions and uses thereof | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-109776522-A | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-21 | — | — | CN | disclosed |
| US-20180222906-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2018-08-09 | — | — | US | disclosed |
| US-9938275-B2 | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170129891-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2017-05-11 | — | — | US | disclosed |
| US-9550773-B2 | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2516379-B1 | HYDROCARBON FEED FLEXIBLE HIGH PRESSURE NITRATION PLANT DESIGN | ANGUS CHEMICAL (US) | 2016-12-28 | — | — | EP | disclosed |
| US-9504933-B2 | Hydrocarbon feed flexible high pressure nitration plant design | ANGUS CHEMICAL COMPANY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150218162-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2015-08-06 | — | — | US | disclosed |
| CN-102741217-B | Design of high pressure nitration plant with flexible hydrocarbon feed | DOW GLOBAL TECHNOLOGIES INC | 2015-04-15 | — | — | CN | disclosed |
| US-20110092477-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2011-04-21 | — | — | US | disclosed |
| US-7884207-B2 | such as 4-[(4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl]tetrahydro-2H-pyran-4-ol, used as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100010250-A1 | METHODS FOR PREPARING 2-METHOXYISOBUTYLISONITRILE AND TETRAKIS(2-METHOXYISOBUTYLISONITRILE)COPPER(I) TETRAFLUOROBORATE | Draximage Limited (IE) | 2010-01-14 | — | — | US | disclosed |
| US-7563920-B2 | Methods for preparing 2-methoxyisobutylisonitrile and tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluoroborate | Draximage Limited (IE) | 2009-07-21 | — | — | US | disclosed |
| US-7563920-B2 | Methods for preparing 2-methoxyisobutylisonitrile and tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluoroborate | Draximage Limited (IE) | 2009-07-21 | — | — | US | disclosed |
| US-20080102028-A1 | METHODS FOR PREPARING 2-METHOXYISOBUTYLISONITRILE AND TETRAKIS(2-METHOXYISOBUTYLISONITRILE)COPPER(I) TETRAFLUOROBORATE | DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) | 2008-05-01 | — | — | US | disclosed |
| US-20080102028-A1 | METHODS FOR PREPARING 2-METHOXYISOBUTYLISONITRILE AND TETRAKIS(2-METHOXYISOBUTYLISONITRILE)COPPER(I) TETRAFLUOROBORATE | DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) | 2008-05-01 | — | — | US | disclosed |
| US-20070287724-A1 | Substituted Imidazoquinolines, Imidazopyridines, and Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-12-13 | — | — | US | disclosed |
| US-4561862-A | Use of selected beta-nitroalkenes as cetane number boosters for diesel fuel | OLIN CORPORATION (US) | 1985-12-31 | — | — | US | disclosed |
| US-3955935-A | ELECTROLYTIC DEPOSITION, DIFFUSION | GENERAL MOTORS CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |