SCHEMBL20206353

SCHEMBL20206353

CCCCCC(=O)N[C@H]1CCC(=O)NCCC(C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 3/20 0.49
▸ ACE2 Q9BYF1 12/20 0.47
▸ ACE P12821 3/20 0.47
▸ FURIN P09958 1/20 0.44
▸ MC4R P32245 2/20 0.44
▸ MC1R Q01726 2/20 0.44
▸ TUBB4A P04350 1/20 0.42
▸ TUBB P07437 1/20 0.42
▸ TUBA3C P0DPH7 1/20 0.42
▸ TUBA1B P68363 1/20 0.42
▸ TUBA4A P68366 1/20 0.42
▸ TUBB4B P68371 1/20 0.42
▸ TUBB3 Q13509 1/20 0.42
▸ TUBB2A Q13885 1/20 0.42
▸ TUBB8 Q3ZCM7 1/20 0.42
▸ TUBA3E Q6PEY2 1/20 0.42
▸ TUBA1A Q71U36 1/20 0.42
▸ TUBA1C Q9BQE3 1/20 0.42
▸ TUBB6 Q9BUF5 1/20 0.42
▸ TUBB2B Q9BVA1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20206238 0.93 TSLP (0.49) TSLPACE2ACEFURINMC4R
SCHEMBL23750043 0.91 TSLP (0.45) TSLPACE2ACEFURINMC4R
SCHEMBL24991116 0.90 TSLP (0.44) TSLPACE2ACEFURINMC4R
SCHEMBL12092675 0.90 MC4R (0.55) TSLPACE2ACEFURINMC4R
SCHEMBL24991154 0.90 TSLP (0.44) TSLPACE2ACEFURINMC4R
SCHEMBL24990017 0.89 TSLP (0.44) TSLPACE2ACEFURINMC4R
SCHEMBL12657418 0.89 MC1R (0.57) TSLPMC4RMC1RTUBB4ATUBB
SCHEMBL21392469 0.89 MC1R (0.57) TSLPMC4RMC1RTUBB4ATUBB
SCHEMBL20206240 0.88 MC1R (0.57) TSLPMC4RMC1RTUBB4ATUBB
SCHEMBL12657668 0.88 MC1R (0.57) TSLPMC4RMC1RTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711039-B2 Melanocortin receptor-specific peptide with C-terminal naphthylalanine PALATIN TECHNOLOGIES, INC. (US) 2020-07-14 — — US disclosed
US-20180148478-A1 Melanocortin Receptor-Specific Peptide with C-Terminal Naphthylalanine PALATIN TECHNOLOGIES INC (US) 2018-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711039-B2 Melanocortin receptor-specific peptide with C-terminal naphthylalanine MC1R, MC3R, MC4R TSLP 624/4885ACE2 3683/4885ACE 3965/4885
US-20180148478-A1 Melanocortin Receptor-Specific Peptide with C-Terminal Naphthylalanine MC1R, MC3R, MC4R TSLP 624/4885ACE2 3683/4885ACE 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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