Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31405834 | 0.84 | CRBN (0.53) | CRBNLMNAKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL1352364 | 0.81 | KDM4E (0.55) | CRBNLMNAKDM4ECYP2C19TSHR | |
| SCHEMBL9471261 | 0.81 | KDM4E (0.55) | CRBNLMNAKDM4ECYP2C19TSHR | |
| SCHEMBL7507233 | 0.78 | KDM4E (0.52) | CRBNLMNAKDM4ECYP2C19TSHR | |
| SCHEMBL11083062 | 0.78 | KDM4E (0.52) | CRBNLMNAKDM4ECYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL10768658 | 0.78 | KDM4E (0.52) | CRBNLMNAKDM4ECYP2C19TSHR | |
| SCHEMBL18377483 | 0.75 | CRBN (0.50) | CRBNLMNAKDM4ECYP2C19TSHR | |
| SCHEMBL5946694 | 0.72 | CRBN (0.39) | CRBN | |
| SCHEMBL1392715 | 0.70 | — | — | |
| SCHEMBL249184 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3835290-A1 | OXADIAZOLINE COMPOUND OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND USE METHOD THEREFOR | Nihon Nohyaku Co., Ltd. (JP) | 2021-06-16 | — | — | EP | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |