Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471261 | 0.97 | KDM4E (0.55) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL1352364 | 0.97 | KDM4E (0.55) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL7507233 | 0.94 | KDM4E (0.52) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL10768658 | 0.94 | KDM4E (0.52) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL20206752 | 0.78 | CRBN (0.48) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL8428770 | 0.73 | LMNA (0.36) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL15250760 | 0.73 | KDM4E (0.50) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL248285 | 0.71 | — | — | |
| SCHEMBL2324941 | 0.69 | — | — | |
| SCHEMBL2691041 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480094-A | PHOTOINITIATOR | TEIJIN LIMITED (JP) | 1984-10-30 | — | — | US | disclosed |
| US-4400519-A | PHOTOPOLYMERIZATION INITIATORS | TEIJIN LIMITED (JP) | 1983-08-23 | — | — | US | disclosed |