SCHEMBL202069

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL203602	0.89	NPC1 (0.50)	NPC1RAB9AKMT2AEPHX2SMN1; SMN2
	SCHEMBL2320663	0.88	HDAC6 (0.47)	NPC1RAB9APPARAHDAC6EPHX2
	SCHEMBL2707199	0.88	NPC1 (0.46)	NPC1RAB9AMEN1KMT2AHDAC6
	SCHEMBL201065	0.86	AKR1B1 (0.46)	NPC1RAB9ADYRK1AAKR1B1TRPV1
	SCHEMBL201165	0.86	NPC1 (0.44)	NPC1RAB9AMEN1KMT2AHDAC6
	SCHEMBL2704604	0.86	NPC1 (0.44)	NPC1RAB9APPARAEPHX2SMN1; SMN2
	SCHEMBL2704597	0.85	NPC1 (0.48)	NPC1RAB9AMEN1KMT2AHDAC6
	SCHEMBL2707226	0.85	EPHX2 (0.44)	NPC1RAB9AHDAC6EPHX2ALOX5
	SCHEMBL204282	0.85	NPC1 (0.64)	NPC1RAB9AMEN1KMT2AEPHX2
	SCHEMBL2704989	0.84	NPC1 (0.38)	NPC1RAB9AMEN1KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.