SCHEMBL202069

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL203602	0.89	NPC1 (0.50)	NPC1RAB9AKMT2AEPHX2SMN1; SMN2
	SCHEMBL2320663	0.88	HDAC6 (0.47)	NPC1RAB9APPARAHDAC6EPHX2
	SCHEMBL2707199	0.88	NPC1 (0.46)	NPC1RAB9AMEN1KMT2AHDAC6
	SCHEMBL2704604	0.86	NPC1 (0.44)	NPC1RAB9APPARAEPHX2SMN1; SMN2
	SCHEMBL201065	0.86	AKR1B1 (0.46)	NPC1RAB9ADYRK1AAKR1B1TRPV1
	SCHEMBL201165	0.86	NPC1 (0.44)	NPC1RAB9AMEN1KMT2AHDAC6
	SCHEMBL2704597	0.85	NPC1 (0.48)	NPC1RAB9AMEN1KMT2AHDAC6
	SCHEMBL2707226	0.85	EPHX2 (0.44)	NPC1RAB9AHDAC6EPHX2ALOX5
	SCHEMBL204282	0.85	NPC1 (0.64)	NPC1RAB9AMEN1KMT2AEPHX2
	SCHEMBL2704989	0.84	NPC1 (0.38)	NPC1RAB9AMEN1KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.