Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325306 | 0.83 | — | — | |
| SCHEMBL20206747 | 0.70 | CRBN (0.33) | KDM4ELMNACYP2C19 | |
| SCHEMBL20207019 | 0.66 | — | — | |
| SCHEMBL16682230 | 0.65 | CRBN (0.41) | LMNA | |
| SCHEMBL19558173 | 0.62 | CRBN (0.40) | — | |
| SCHEMBL20402375 | 0.60 | — | — | |
| SCHEMBL20841455 | 0.60 | CRBN (0.30) | — | |
| SCHEMBL23011238 | 0.60 | KDM4E (0.32) | KDM4ELMNACYP2C19TSHRNPSR1 | |
| SCHEMBL23160891 | 0.58 | TSHR (0.34) | KDM4ETSHRNPSR1 | |
| SCHEMBL31475490 | 0.58 | TDP1 (0.56) | KDM4ELMNACYP2C19TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |