Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 19/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206934 | 0.99 | DUT (0.45) | DUTPOLBKMT2A | |
| SCHEMBL20206994 | 0.97 | DUT (0.46) | DUTPOLBKMT2A | |
| SCHEMBL20206935 | 0.88 | DUT (0.50) | DUTPOLBKMT2A | |
| SCHEMBL21315543 | 0.86 | DUT (0.60) | DUT | |
| SCHEMBL21315536 | 0.84 | DUT (0.58) | DUT | |
| SCHEMBL20191198 | 0.84 | DUT (0.58) | DUT | |
| SCHEMBL21315540 | 0.82 | DUT (0.55) | DUT | |
| SCHEMBL20190459 | 0.82 | DUT (0.55) | DUT | |
| SCHEMBL20207648 | 0.82 | DUT (0.47) | DUT | |
| SCHEMBL20201858 | 0.82 | DUT (0.47) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |