Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207300 | 0.90 | APLNR (0.78) | APLNR | |
| SCHEMBL20207444 | 0.89 | APLNR (0.65) | APLNR | |
| SCHEMBL20188787 | 0.87 | APLNR (1.00) | APLNR | |
| SCHEMBL20207323 | 0.84 | APLNR (0.76) | APLNR | |
| SCHEMBL20207446 | 0.80 | APLNR (0.77) | APLNR | |
| SCHEMBL20189479 | 0.78 | APLNR (0.86) | APLNR | |
| SCHEMBL20188381 | 0.77 | APLNR (1.00) | APLNR | |
| SCHEMBL20207282 | 0.77 | APLNR (0.72) | APLNR | |
| SCHEMBL22537274 | 0.75 | APLNR (0.77) | APLNR | |
| SCHEMBL20189712 | 0.74 | APLNR (1.00) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541805-B1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018097945-A1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |