Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537311 | 0.90 | APLNR (0.73) | APLNR | |
| SCHEMBL20207291 | 0.88 | APLNR (0.72) | APLNR | |
| SCHEMBL20189106 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL20188939 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL20188937 | 0.85 | APLNR (1.00) | APLNR | |
| SCHEMBL22537310 | 0.83 | APLNR (0.62) | APLNR | |
| SCHEMBL22537161 | 0.82 | APLNR (0.58) | APLNR | |
| SCHEMBL22537275 | 0.82 | APLNR (0.72) | APLNR | |
| Hydrogen Sulfide SCHEMBL20207482 | 0.82 | APLNR (0.56) | APLNR | |
| SCHEMBL22537178 | 0.79 | APLNR (0.73) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097945-A1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |