Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207519 | 0.82 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL20203615 | 0.82 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL14994327 | 0.72 | GAA (0.37) | MEN1KMT2AKDM4E | |
| SCHEMBL25022837 | 0.71 | KDM4E (0.32) | MEN1KMT2AKDM4E | |
| SCHEMBL18314634 | 0.69 | LMNA (0.41) | MEN1KMT2AKDM4E | |
| SCHEMBL9910955 | 0.69 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL29545354 | 0.69 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL19744117 | 0.68 | KMT2A (0.42) | MEN1KMT2AKDM4E | |
| SCHEMBL26307238 | 0.68 | — | — | |
| SCHEMBL4076222 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097295-A1 | CRYSTAL OF PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE OR SOLVATE THEREOF | 帝人ファーマ株式会社 | 2018-05-31 | — | — | WO | disclosed |