Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 13/20 | 0.55 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201978 | 0.87 | DUT (0.49) | DUTIDH1PDE4BGRM2 | |
| SCHEMBL29387191 | 0.86 | DUT (0.74) | DUT | |
| SCHEMBL20351630 | 0.86 | DUT (0.74) | DUT | |
| SCHEMBL20188154 | 0.86 | DUT (0.74) | DUT | |
| SCHEMBL18374227 | 0.86 | DUT (0.74) | DUT | |
| SCHEMBL20201767 | 0.82 | DUT (0.60) | DUT | |
| SCHEMBL22751349 | 0.82 | DUT (0.64) | DUT | |
| SCHEMBL20202048 | 0.82 | DUT (0.64) | DUT | |
| SCHEMBL20207742 | 0.81 | DUT (0.62) | DUT | |
| SCHEMBL20201771 | 0.80 | DUT (0.77) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |