Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 9/20 | 0.47 |
| ▸ | ACHE | P22303 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20376628 | 0.89 | DUT (0.43) | DUTACHE | |
| SCHEMBL18374264 | 0.87 | DUT (0.60) | DUT | |
| SCHEMBL20201674 | 0.82 | DUT (0.52) | DUT | |
| SCHEMBL20207742 | 0.82 | DUT (0.62) | DUT | |
| SCHEMBL20191015 | 0.81 | DUT (0.69) | DUT | |
| SCHEMBL20338535 | 0.81 | DUT (0.69) | DUT | |
| SCHEMBL20201677 | 0.81 | DUT (0.51) | DUT | |
| SCHEMBL20338536 | 0.81 | DUT (0.69) | DUT | |
| SCHEMBL20191013 | 0.81 | DUT (0.69) | DUT | |
| SCHEMBL20207866 | 0.81 | DUT (0.47) | DUTALDH1A1LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |