Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204880 | 0.92 | SCN9A (0.39) | SCN9AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL21325346 | 0.82 | HTR2A (0.37) | SCN9AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL20202027 | 0.82 | SCN9A (0.36) | SCN9AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL21325052 | 0.82 | HTR2A (0.37) | SCN9AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL20201456 | 0.80 | MAOA (0.53) | SCN9AHTR2AHTR2CHTR2BSLC18A2 | |
| SCHEMBL21325051 | 0.77 | HTR2A (0.36) | SCN9AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL22751279 | 0.77 | SLC18A2 (0.36) | SCN9AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL20201840 | 0.75 | CA7 (0.46) | SCN9ASCN5A | |
| SCHEMBL21324950 | 0.72 | CA7 (0.44) | SCN9ASCN5A | |
| SCHEMBL21533822 | 0.72 | CA7 (0.44) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |