Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207970 | 0.86 | MRGPRX4 (0.43) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL15085817 | 0.82 | TSHR (0.60) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL18374087 | 0.82 | CYP2C9 (0.45) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL20208353 | 0.82 | TDP1 (0.38) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL764961 | 0.80 | MAPT (0.46) | CYP2C9SMN1; SMN2TSHRTDP1MAPT | |
| SCHEMBL19598860 | 0.80 | CYP4F2 (0.36) | TDP1L3MBTL1MCHR1PDE2AIDO1 | |
| SCHEMBL12958155 | 0.79 | MAPT (0.56) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL8251583 | 0.79 | L3MBTL1 (0.47) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL4317147 | 0.79 | TSHR (0.44) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 | |
| SCHEMBL15085872 | 0.79 | SMN1; SMN2 (0.51) | CYP2C9SMN1; SMN2CYP1A2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097057-A1 | 5-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY | GENZYME CORPORATION (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |