Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204761 | 0.81 | HCAR2 (0.35) | HCAR2LNPEPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15787189 | 0.76 | TAAR1 (0.40) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL20201906 | 0.72 | TAAR1 (0.37) | HCAR2LNPEPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20207798 | 0.72 | CYP2C19 (0.38) | — | |
| SCHEMBL12433605 | 0.70 | SIRT2 (0.36) | — | |
| SCHEMBL20204829 | 0.69 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9294596 | 0.68 | HRH3 (0.35) | NMT1 | |
| SCHEMBL9294600 | 0.68 | HRH3 (0.35) | NMT1 | |
| SCHEMBL9485467 | 0.68 | TYR (0.39) | CEL | |
| SCHEMBL12433616 | 0.67 | SLC6A2 (0.32) | LNPEPSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |