Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255051 | 0.82 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20207515 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3OPRL1 | |
| SCHEMBL19658854 | 0.77 | TYR (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17188320 | 0.75 | ALDH1A1 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11942564 | 0.75 | ALOX5 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14386019 | 0.74 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3CHRM3 | |
| SCHEMBL13850100 | 0.74 | ALOX5 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13763 | 0.74 | MPO (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20201906 | 0.73 | TAAR1 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12706482 | 0.73 | CEL (0.35) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |