Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD2 | P13995 | 13/20 | 0.48 |
| ▸ | MTHFD1 | P11586 | 9/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208628 | 1.00 | MTHFD2 (0.48) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| SCHEMBL24691316 | 1.00 | MTHFD2 (0.48) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL21354086 | 0.99 | MTHFD2 (0.47) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| SCHEMBL20209028 | 0.89 | MTHFD2 (0.51) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL21354111 | 0.88 | MTHFD2 (0.51) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| SCHEMBL20209030 | 0.84 | MTHFD2 (0.51) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| SCHEMBL21354101 | 0.83 | MTHFD2 (0.44) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL21354084 | 0.83 | MTHFD2 (0.50) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| SCHEMBL20209040 | 0.80 | ERN1 (0.41) | MTHFD2MTHFD1ERN1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL21354112 | 0.79 | ERN1 (0.41) | MTHFD2MTHFD1ERN1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3546463-A1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | Daiichi Sankyo Co., Ltd. (JP) | 2019-10-02 | — | — | EP | disclosed |
| WO-2018097162-A1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | 第一三共株式会社 | 2018-05-31 | — | — | WO | disclosed |