Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21050252 | 0.83 | PRKD3 (0.42) | ADORA1ADORA2APRKD3MAPK8MAPK9 | |
| SCHEMBL20208720 | 0.78 | CDK5 (0.45) | ADORA1ADORA2APRKD3MAPK8MAPK9 | |
| SCHEMBL29661338 | 0.78 | ADORA1 (0.43) | ADORA1ADORA2AALDH1A1LMNANOS1 | |
| SCHEMBL20208862 | 0.78 | CDK5 (0.44) | ADORA1ADORA2APRKD3MAPK8MAPK9 | |
| SCHEMBL25768308 | 0.78 | CDK5 (0.58) | CDK5CDK5R1 | |
| SCHEMBL20806161 | 0.76 | CDK5 (0.43) | ADORA1ADORA2APRKD3MAPK8MAPK9 | |
| SCHEMBL4777464 | 0.74 | ADORA1 (0.41) | ADORA1ADORA2ACDK5CDK5R1ALDH1A1 | |
| SCHEMBL30590049 | 0.74 | ADORA1 (0.41) | ADORA1ADORA2ACDK5CDK5R1ALDH1A1 | |
| SCHEMBL22020964 | 0.74 | CDK5 (0.41) | ADORA1ADORA2APRKD3MAPK8MAPK9 | |
| SCHEMBL29665061 | 0.73 | ADORA1 (0.40) | ADORA1ADORA2ACDK5CDK5R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098264-A1 | COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2018-05-31 | — | — | WO | disclosed |