SCHEMBL20208879

SCHEMBL20208879

CN1PO[C@@]2(C)CCCC[C@H]12

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20190820 0.64 GAA (0.33) GAA
SCHEMBL20190502 0.64 GAA (0.33) GAA
SCHEMBL25970459 0.64 GAA (0.33) GAA
SCHEMBL14087223 0.64
SCHEMBL7108599 0.64
SCHEMBL1262673 0.64
SCHEMBL19256280 0.63
SCHEMBL7924351 0.61 GAA (0.44) GAAKDM4E
Methyl Alcohol SCHEMBL3833898 0.61 CYP3A4 (0.43) GAAKDM4E
Chloromethane SCHEMBL4688989 0.61 CYP3A4 (0.39) GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098264-A1 COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2018-05-31 WO disclosed