SCHEMBL20190502

SCHEMBL20190502

CN1[C@@H]2CCCC[C@@]2(C)OP1Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25970459 1.00 GAA (0.33) GAA
SCHEMBL20190820 1.00 GAA (0.33) GAA
SCHEMBL25970647 0.78 GAA (0.30) GAA
SCHEMBL25970666 0.78 GAA (0.30) GAA
SCHEMBL25970158 0.75
SCHEMBL25969828 0.75
SCHEMBL25969670 0.70 SLC6A2 (0.40)
SCHEMBL25969649 0.70 SLC6A2 (0.40)
SCHEMBL25969658 0.70 SLC6A2 (0.40)
SCHEMBL25969640 0.70 SLC6A2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD (SG) 2026-02-26 US disclosed
US-12473321-B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis WAVE LIFE SCIENCES LTD. (SG) 2025-11-18 US disclosed
US-12428442-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2025-09-30 US disclosed
US-20240368207-A1 COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2024-11-07 US disclosed
US-20240174710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2024-05-30 US disclosed
US-11873316-B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis WAVE LIFE SCIENCES LTD. (SG) 2024-01-16 US disclosed
US-11873316-B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis WAVE LIFE SCIENCES LTD. (SG) 2024-01-16 US disclosed
US-11873316-B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis WAVE LIFE SCIENCES LTD. (SG) 2024-01-16 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 US disclosed
US-20220356204-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2022-11-10 US disclosed
EP-3642182-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS Wave Life Sciences Ltd. (SG) 2020-04-29 EP disclosed
EP-3544987-A1 COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS Wave Life Sciences Ltd. (SG) 2019-10-02 EP disclosed
WO-2018237194-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2018-12-27 WO disclosed
WO-2018098264-A1 COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2018-05-31 WO disclosed
WO-2018098264-A1 COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718638-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT GAA 624/4885
US-11873316-B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis RNGTT, POLI, FBL GAA 1328/4885
US-20220356204-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS ALKBH1, DUT, RNGTT GAA 624/4885
US-20240368207-A1 COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE AND OLIGONUCLEOTIDE SYNTHESIS RNGTT, POLI, FBL GAA 1328/4885
US-12428442-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT GAA 624/4885
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS NSUN2, NSUN3, NOP2 GAA 3136/4885
US-20240174710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS ALKBH1, DUT, RNGTT GAA 624/4885
US-12473321-B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis RNGTT, POLI, FBL GAA 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.