Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208944 | 0.97 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20208799 | 0.92 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20208800 | 0.89 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20208740 | 0.88 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20208958 | 0.88 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL22812507 | 0.86 | DHODH (0.34) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL22145831 | 0.85 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20208802 | 0.84 | CHEK2 (0.30) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20208946 | 0.83 | ALDH1A1 (0.34) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL20209195 | 0.82 | ALDH1A1 (0.31) | ALDH1A1HPGDKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |