Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22812439 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL22812410 | 0.91 | KDM4E (0.38) | KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL20208706 | 0.91 | KDM4E (0.40) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL20208701 | 0.90 | KDM4E (0.39) | KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL20208702 | 0.87 | KDM4E (0.35) | KDM4EATML3MBTL1 | |
| SCHEMBL20208707 | 0.87 | KDM4E (0.37) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL22812390 | 0.86 | TSPO (0.34) | KDM4EATML3MBTL1 | |
| SCHEMBL20208712 | 0.85 | KDM4E (0.37) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL20208966 | 0.84 | KDM4E (0.36) | KDM4EATML3MBTL1 | |
| SCHEMBL20208735 | 0.83 | ATM (0.33) | KDM4EATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |