Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208970 | 0.88 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL20208978 | 0.88 | — | — | |
| SCHEMBL20208653 | 0.83 | — | — | |
| SCHEMBL20208797 | 0.83 | ALDH1A1 (0.39) | KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22812600 | 0.83 | KDM4E (0.40) | KDM4EL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL20208801 | 0.83 | HSD17B10 (0.38) | ACHEALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20208630 | 0.82 | P2RX4 (0.30) | — | |
| SCHEMBL22812481 | 0.82 | ALDH1A1 (0.37) | KDM4EL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL22812439 | 0.81 | KDM4E (0.41) | KDM4EL3MBTL1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL22812405 | 0.80 | KDM4E (0.30) | KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |