SCHEMBL20209658

SCHEMBL20209658

CCCNc1ccc(CCc2ccc(-c3ccc(C4CCC(C(N)CC)CC4)cc3F)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.35
APP P05067 2/20 0.33
SPHK1 Q9NYA1 4/20 0.33
RARB P10826 1/20 0.33
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
FFAR4 Q5NUL3 6/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18559004 0.89 APP (0.37) FASNAPPCYP3A4CYP2C9CYP2D6
SCHEMBL18459106 0.89 APP (0.37) FASNAPPCYP3A4CYP2C9CYP2D6
SCHEMBL20209657 0.88 APP (0.36) FASNAPPSPHK1RARBCYP3A4
SCHEMBL20209659 0.87 APP (0.36) FASNAPPSPHK1RARBCYP3A4
SCHEMBL20209854 0.86 FASN (0.45) FASNAPPSPHK1RARBCYP3A4
SCHEMBL20209656 0.85 FASN (0.37) FASNAPPSPHK1RARBCYP3A4
SCHEMBL18458594 0.83 FASN (0.40) FASNAPPSPHK1CYP3A4CYP2C9
SCHEMBL18458593 0.80 APP (0.41) FASNAPPSPHK1CYP3A4CYP2C9
SCHEMBL19229037 0.80 APP (0.35) FASNAPPCYP3A4CYP2C9CYP2D6
SCHEMBL18458840 0.80 APP (0.36) FASNAPPCYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed