SCHEMBL20209657

SCHEMBL20209657

CCc1ccc(CCc2ccc(-c3ccc(C4CCC(C(N)CC)CC4)cc3F)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.36
FASN P49327 1/20 0.35
CYP3A4 P08684 3/20 0.34
CYP2C9 P11712 2/20 0.34
RARB P10826 1/20 0.34
FFAR4 Q5NUL3 6/20 0.33
SPHK1 Q9NYA1 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
DPP4 P27487 4/20 0.31
DPP9 Q86TI2 2/20 0.31
DPP7 Q9UHL4 2/20 0.31
DPP8 Q6V1X1 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20209659 0.92 APP (0.36) APPFASNCYP3A4CYP2C9RARB
SCHEMBL20209658 0.88 FASN (0.35) APPFASNCYP3A4CYP2C9RARB
SCHEMBL18458593 0.85 APP (0.41) APPFASNCYP3A4CYP2C9SPHK1
SCHEMBL18458840 0.85 APP (0.36) APPFASNCYP3A4CYP2C9CYP2D6
SCHEMBL20202974 0.83 FASN (0.47) APPFASNCYP3A4CYP2C9RARB
SCHEMBL20209858 0.82 FASN (0.38) APPFASNCYP3A4CYP2C9RARB
SCHEMBL9664291 0.82 FASN (0.38) APPFASNCYP3A4CYP2C9RARB
SCHEMBL24372634 0.82 CYP2C9 (0.43) APPFASNCYP3A4CYP2C9CYP2D6
SCHEMBL18866787 0.82 FASN (0.41) APPFASNCYP3A4CYP2C9CYP2D6
SCHEMBL20202980 0.82 CYP3A4 (0.49) APPFASNCYP3A4CYP2C9RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed