SCHEMBL20209759

SCHEMBL20209759

CCCNc1ccc(CCc2ccc(-c3ccc(-c4ccc(C)cc4)cc3F)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.43
▸ FFAR1 O14842 2/20 0.41
▸ RARB P10826 3/20 0.41
▸ RARA P10276 1/20 0.38
▸ RARG P13631 1/20 0.38
▸ PDE3B Q13370 1/20 0.38
▸ PDE3A Q14432 1/20 0.38
▸ AURKA O14965 1/20 0.37
▸ ABL1 P00519 1/20 0.37
▸ NTRK1 P04629 1/20 0.37
▸ LCK P06239 1/20 0.37
▸ CSF1R P07333 1/20 0.37
▸ RET P07949 1/20 0.37
▸ MET P08581 1/20 0.37
▸ PDGFRB P09619 1/20 0.37
▸ PIM1 P11309 1/20 0.37
▸ PDGFRA P16234 1/20 0.37
▸ FLT3 P36888 1/20 0.37
▸ MAPK8 P45983 1/20 0.37
▸ CDK8 P49336 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20209758 0.91 RARB (0.41) MAPTRARBRARARARGMEN1
SCHEMBL18458494 0.86 RARB (0.39) MAPTRARBRARARARGMEN1
SCHEMBL20202985 0.86 RARB (0.46) FFAR1RARBRARARARGPDE3B
SCHEMBL20202983 0.86 RARB (0.46) FFAR1RARBRARARARGPDE3B
SCHEMBL19820862 0.86 PDE3B (0.46) FFAR1RARBRARARARGPDE3B
SCHEMBL20209584 0.86 MAPT (0.55) MAPTFFAR1AURKAABL1NTRK1
SCHEMBL14175171 0.84 RARB (0.47) FFAR1RARBRARARARGPDE3B
SCHEMBL17614866 0.84 RARB (0.47) FFAR1RARBRARARARGPDE3B
SCHEMBL12333085 0.84 RARB (0.47) FFAR1RARBRARARARGPDE3B
SCHEMBL20209760 0.83 PDE3B (0.45) FFAR1RARBRARARARGPDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 — — US disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 — — US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 — — US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 — — US disclosed
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